Robert L Hudkins Selected Research

6- (4- (3- (2- methylpyrrolidin- 1- yl)propoxy)phenyl)- 2H- pyridazin- 3- one

1/2012	CEP-26401 (irdabisant), a potent and selective histamine H₃ receptor antagonist/inverse agonist with cognition-enhancing and wake-promoting activities.
7/2011	Discovery and characterization of 6-{4-[3-(R)-2-methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, irdabisant): a potent, selective histamine H3 receptor inverse agonist.

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Robert L Hudkins Research Topics

Disease

3	Neoplasms (Cancer) 12/2016 - 12/2003
1	Non-alcoholic Fatty Liver Disease 12/2016
1	Obesity 12/2016
1	Sleep Wake Disorders 01/2016
1	Schizophrenia (Dementia Praecox) 01/2012
1	Cognitive Dysfunction 07/2011
1	Central Nervous System Diseases (CNS Diseases) 01/2010
1	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 02/2006
1	Leukemia 02/2006
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2002
1	Alzheimer Disease (Alzheimer's Disease) 01/2002

Drug/Important Bio-Agent (IBA)

2	6- (4- (3- (2- methylpyrrolidin- 1- yl)propoxy)phenyl)- 2H- pyridazin- 3- oneIBA 01/2012 - 07/2011
1	Biological ProductsIBA 12/2016
1	3- (1'- cyclobutylspiro(4H- 1,3- benzodioxine- 2,4'- piperidine)- 6- yl)- 5,5- dimethyl- 1,4- dihydropyridazin- 6- oneIBA 01/2016
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2012
1	CytokinesIBA 01/2012
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2012
1	Antipsychotic Agents (Antipsychotics)IBA 01/2012
1	Histamine (Histamine Dihydrochloride)FDA Link 07/2011
1	Histamine H3 AntagonistsIBA 01/2010
1	Anaplastic Lymphoma KinaseIBA 02/2006
1	Proteins (Proteins, Gene)FDA Link 02/2006
1	dimethylglycineIBA 12/2003
1	EstersIBA 12/2003
1	ProdrugsIBA 12/2003
1	compound 21IBA 12/2003
1	Transcription Factors (Transcription Factor)IBA 01/2002
1	Phosphotransferases (Kinase)IBA 01/2002
1	3,9-bis((ethylthio)methyl)-K-252aIBA 01/2002

Therapy/Procedure

2	Therapeutics 01/2012 - 01/2012